ADHD Medication During Pregnancy and Breastfeeding
Women suffering from ADHD have to make a difficult choice regarding whether or not to stop taking ADHD medication during pregnancy and breastfeeding. There isn't much information on how long-term exposure to these drugs could affect the fetus.
A recent study published in Molecular Psychiatry demonstrates that children exposed to ADHD medication during pregnancy do not develop neurological disorders like hearing loss or vision, febrile seizures, or IQ impairment. The authors acknowledge that further high-quality studies are needed.
Risk/Benefit Analysis
Pregnant women who take ADHD medications need to balance the benefits of using them against the risks to the foetus. Physicians do not have the data needed to provide clear recommendations however they can provide information regarding benefits and risks that can help pregnant women make informed choices.
A study published in Molecular Psychiatry concluded that women who were taking ADHD medication during their early pregnancy did not have a greater risk of fetal malformations or structural birth defects. Researchers conducted a large population-based case control study to examine the prevalence of major structural defects in infants born to mothers who took stimulants during pregnancy. Pediatric cardiologists and clinical geneticists looked over the cases to ensure accurate classification of the cases and to reduce the chance of bias.
However, the researchers' study had its limitations. The researchers were not able, in the first place to distinguish the effects triggered by the medication from the disorder. This limitation makes it difficult for researchers to determine whether the few associations observed between the groups that were exposed to the use of medications, or if they were confounded by the presence of comorbidities. The researchers also did not look at the long-term effects for the offspring.
The study did find that infants whose mothers had taken ADHD medication during pregnancy were at a slightly more risk of being admitted to the neonatal intensive care unit (NICU) than those whose mothers had not taken any medication or taken off their medication prior to or during pregnancy. The reason for this was central nervous system disorders, and the increased risk of admission was not found to be affected by the type of stimulant medications were taken during pregnancy.
Women who took stimulant ADHD medications during pregnancy also had a higher chance of having to have an emergency caesarean section or having one whose baby scored low on the Apgar scale (less than 7). These increases appeared to be independent of the type of medication used during pregnancy.
Researchers suggest that the small risk of using ADHD medications in early pregnancies could be offset by the more beneficial outcomes for both baby and mother of continued treatment for the woman's disorder. Physicians should talk to their patients about this issue and, if possible, help them develop coping skills that can lessen the impact of her disorder in her daily life and relationships.
Medication Interactions
As more women than ever are diagnosed with ADHD and being treated with medication, the question of whether or not to discontinue treatment during pregnancy is one that doctors are having to face. These decisions are usually made without clear and authoritative evidence. Instead, doctors must weigh their own knowledge in conjunction with the experiences of other doctors and the research on the subject.
The issue of risk for infants can be difficult to determine. Many of the studies on this subject are based on observational data rather than controlled research, and their conclusions are often contradictory. most popular adhd medication studies focus on live births, which can underestimate the severity of teratogenic effects leading to abortions or terminations of pregnancy. The study presented in this journal club addresses these issues by analyzing data on live and deceased births.
The conclusion is that while certain studies have demonstrated that there is a positive correlation between ADHD medications and the risk of certain birth defects, others have found no such relationship and the majority of studies demonstrate a neutral or slightly negative impact. In the end, a careful risk/benefit assessment must be conducted in every instance.
For many women with ADHD and ADD, the decision to stop taking medication is difficult if not impossible. In a recent piece published in Archives of Women's Mental Health by psychologist Jennifer Russell, she notes that stopping ADHD medications during pregnancy can cause depression and feelings of loneliness. A loss of medication may also impact the ability to drive safely and perform work-related tasks, which are crucial aspects of everyday life for people with ADHD.
She recommends women who are uncertain about whether or not to discontinue medication due to their pregnancy consider informing family members, friends and colleagues on the condition, its effects on daily functioning, and on the benefits of keeping the current treatment plan. It will also help a woman feel confident about her decision. Some medications can my general practitioner prescribe adhd medication pass through the placenta. If a patient decides to not take her ADHD medication while pregnant and breastfeeding, it is crucial to be aware that the medication may be transferred to her infant.
Risk of Birth Defects
As the use of ADHD drugs to treat symptoms of attention deficit hyperactivity disorder (ADHD) increases, so do concerns about what impact the medications prescribed for adhd could have on fetuses. Recent research published in the journal Molecular Psychiatry has added to the body of knowledge regarding this issue. Researchers used two massive datasets to analyze more than 4.3 million pregnancies and determine if stimulant medication use caused birth defects. Researchers found that while the overall risk is low, the first trimester ADHD exposure to medication was associated with slightly higher risk of specific heart defects such as ventriculoseptal defect.
The authors of the study did not discover any connection between early use of medication and other congenital anomalies like facial deformities, or club feet. The results are consistent with previous studies showing the presence of a small, but significant increase in the risk of cardiac malformations in women who started taking ADHD medications prior to the time of the birth of their child. The risk grew in the latter half of pregnancy, when a lot of women decide to stop taking their ADHD medication.
Women who used adhd medication Prescription Uk medications during the first trimester of their pregnancy were also more likely to have a caesarean section, a low Apgar score after delivery and a baby who needed breathing assistance at birth. The researchers of the study could not eliminate selection bias because they restricted the study to women without other medical conditions that could have contributed to the findings.
The researchers hope that their research will serve to inform the clinical decisions of doctors who see pregnant women. The researchers recommend that, while discussing benefits and risks are crucial, the decision regarding whether or not to stop medication should be according to the severity of each woman's ADHD symptoms and the needs of the woman.
The authors also caution that even though stopping the medication is an option, it is not an option that is recommended due to the high incidence of depression and other mental health problems among women who are pregnant or post-partum. Further, the research suggests that women who choose to stop their medications are more likely to experience difficulties adapting to life without them following the baby's arrival.
Nursing
The responsibilities of a new mother can be overwhelming. Women with ADHD can face severe challenges when they have to manage their symptoms, go to doctor appointments and prepare for the birth of their child and adjust to a new routine. This is why many women decide to continue taking their ADHD medications throughout the course of pregnancy.
The majority of stimulant medications are absorbed by breast milk in low quantities, so the risk to infant who is breastfeeding is low. However, the rate of exposure to medication by the newborn can vary depending on dosage, how often it is administered and the time of the day it is administered. In addition, different medications enter the baby’s system through the gastrointestinal tract or through breast milk. The effect on the health of a newborn isn't fully comprehended.
Due to the absence of evidence, some doctors may be inclined to discontinue stimulant medications during the pregnancy of a woman. This is a difficult decision for the patient, who must weigh the benefits of continuing her medication against the potential risks to the fetus. As long as there is no more information, doctors should ask all pregnant patients about their history of ADHD and if they are taking or planning to take medication during the perinatal period.
Many studies have shown that women can continue taking their ADHD medication without risk while breastfeeding and during pregnancy. In response, a growing number of patients are opting to continue their medication. They have discovered after consulting with their physicians that the benefits of retaining their current medication outweigh any potential risks.
Women who suffer from ADHD who are planning to nurse should seek the advice of a specialist psychiatrist before becoming pregnant. They should review their medications with their doctor and discuss the pros and cons of continued treatment, including non stimulant adhd medication uk-pharmacological strategies. Psychoeducation should also be offered to help pregnant women suffering from ADHD understand their symptoms and the root cause and learn about treatment options and strengthen existing strategies for managing. This should be a multidisciplinary approach including obstetricians, GPs and psychiatry. Pregnancy counseling should consist of a discussion of a treatment plan for the mother and the child, monitoring of indicators of deterioration, and, if necessary, adjustments to the medication regime.